The authors have compiled into a practical text their experiences encompassing over 20 years of work in the rehabilitation of patients in a persistent vegetative state. In addition to the partial or complete recovery of mental and neurological functions, another condition has been gaining in recognition in recent years: the state of minimal responder, which they elucidate in their book. This title bridges a gap in the specialized literature by providing neurologists, emergency physicians, physiatrists, and internists, as well as therapists, with a new set of tools to aid them in obtaining more rapid progress in the treatment of these patients, whose improvement is wholly dependent upon them. A second equally relevant aspect considered is the relationship of the care-giving physician with the patient's family. Particular attention is given to the approach the physician must take towards family members of the patient lacking mental activity. A third part illustrates the structural and instrumental devices useful in planning and operating a unit specialized in the treatment of patients in the persistent vegetative state, with particular attention given to the rules governing the unit.